Skip Navigation


JAC Advance Access originally published online on November 12, 2003
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
52/6/890    most recent
dkh011v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (11)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Moore, J. P.
Right arrow Articles by Shattock, R. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Moore, J. P.
Right arrow Articles by Shattock, R. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?


Journal of Antimicrobial Chemotherapy (2003) 52, 890-892
© 2003 The British Society for Antimicrobial Chemotherapy

Leading Article

Preventing HIV-1 sexual transmission—not sexy enough science, or no benefit to the bottom line?

John P. Moore1,* and Robin J. Shattock2

1 Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, USA; 2 Department of Cellular and Molecular Medicine, Infectious Diseases, St. George’s Hospital Medical School, London, UK

Keywords: HIV, microbicides, transmission

The first 150 words of the full text of this article appear below.

In the continued, and likely to be prolonged, absence of an effective vaccine, the scientific community needs to find an alternative way to prevent the sexual transmission of human immunodeficiency virus type 1 (HIV-1). The global HIV-1 epidemic is fuelled by heterosexual transmission, which is how about 80% of the 40 million people now infected acquired this lethal virus.1 Most (~95%) new infections now occur in the developing world, almost half among women.1 Although HIV-1 infection is not particularly easy to acquire sexually, the lengthy duration of asymptomatic infection, the high frequency with which at least some people have sexual intercourse, and various exacerbating circumstances, all conspire to render HIV-1 readily transmissible in the long run. What can be done about this? Education and condom distribution play important roles in reducing transmission, but sexual behaviour is notoriously difficult to modify, particularly among young people, and there are often cultural . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Virol.Home page
H.-T. Ho, L. Fan, B. Nowicka-Sans, B. McAuliffe, C.-B. Li, G. Yamanaka, N. Zhou, H. Fang, I. Dicker, R. Dalterio, et al.
Envelope conformational changes induced by human immunodeficiency virus type 1 attachment inhibitors prevent CD4 binding and downstream entry events.
J. Virol., April 1, 2006; 80(8): 4017 - 4025.
[Abstract] [Full Text] [PDF]

Home page
 J Antimicrob ChemotherHome page
R. K. Malcolm, A. D. Woolfson, C. F. Toner, R. J. Morrow, and S. D. McCullagh
Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings
J. Antimicrob. Chemother., November 1, 2005; 56(5): 954 - 956.
[Abstract] [Full Text] [PDF]