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JAC Advance Access originally published online on September 12, 2003
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Journal of Antimicrobial Chemotherapy (2003) 52, 732
© 2003 The British Society for Antimicrobial Chemotherapy

Correspondence

Overstretching the mutant prevention concentration

David M. Livermore*

Antibiotic Resistance Monitoring and Reference Laboratory, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK

Keywords: resistance, selection pressure, mutation

The first 10% of the full text of this article appears below.

Sir,

Smith et al.1 make the good point that mutant prevention concentrations (MPCs, i.e. those drug levels that inhibit first-step mutants, militating against their . . . [Full Text of this Article]


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