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JAC Advance Access originally published online on April 25, 2003
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Journal of Antimicrobial Chemotherapy (2003) 51, 1435-1436
© 2003 The British Society for Antimicrobial Chemotherapy


Correspondence

Aromatic alcohols and their effect on Gram-negative bacteria, cocci and mycobacteria

S. Fraud1, E. L. Rees1, E. Mahenthiralingam2, A. D. Russell1,* and J.-Y. Maillard1,§

1 Welsh School of Pharmacy and 2 School of Molecular and Medical Biosciences, Cardiff University, Cardiff CF10 3XF, UK

Keywords: aromatic alcohols, mycobacteria, Gram-positives, Gram-negatives

The first 10% of the full text of this article appears below.

Sir,

Phenethyl alcohol (2-phenylethanol; PEA, mol. wt 122.17) inhibits a range of Gram-negative bacteria, but not Pseudomonas fluorescens, at a concentration of 0.2% (2000 mg/L), whereas Gram-positive cocci, such as Staphylococcus aureus are inhibited at 0.5% w/v (5000 mg/L), with Enterococcus faecalis requiring still higher concentrations.1 PEA-containing media had earlier been suggested as a means of selecting for Gram-positive bacteria in mixed flora.2 Interestingly, Mycobacterium smegmatis and Mycobacterium phlei were also inhibited at 0.2%, suggesting that . . . [Full Text of this Article]

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