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JAC Advance Access originally published online on January 6, 2003
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Journal of Antimicrobial Chemotherapy (2003) 51, 431-433
© 2003 The British Society for Antimicrobial Chemotherapy

Antifungal susceptibility patterns of yeast isolates causing bloodstream infections

Francesco Barchiesi1,*, Giuseppina Caggiano2, Monia Maracci1, Daniela Arzeni1, Giorgio Scalise1 and Maria Teresa Montagna2

1 Istituto di Malattie Infettive e Medicina Pubblica, Università degli Studi di Ancona, Azienda Ospedaliera Umberto I°, Via Conca 60020, Torrette di Ancona, Ancona; 2 Dipartimento di Medicina Interna e Medicina Pubblica, Sezione Igiene, Università degli Studi di Bari, Italy

Received 29 July 2002; returned 6 October 2002; revised 31 October 2002; accepted 4 November 2002

A broth microdilution method following the NCCLS recommendations was used for testing fluconazole, itraconazole, posaconazole, 5-fluorocytosine and amphotericin B against 83 yeast isolates causing bloodstream infections in 59 patients hospitalized between January 1998 and June 2001 at the University Hospital of Bari, Italy. Isolates belonged to four species of Candida and three other yeast genera. Of the isolates, 97%, 95% and 100% were susceptible to fluconazole, itraconazole and posaconazole, respectively. Similarly, 97% and 100% of the isolates were susceptible to 5-fluorocytosine and amphotericin B, respectively.

Keywords: antifungal susceptibility, yeast isolates

* Corresponding author. Tel: +39-071-5963467; Fax: +39-071-5963468; E-mail: cmalinf{at}popcsi.unian.it


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