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JAC Advance Access originally published online on December 12, 2002
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Journal of Antimicrobial Chemotherapy (2003) 51, 196-199
© 2003 The British Society for Antimicrobial Chemotherapy


Correspondence

Activity of faropenem, a new furanem, against European respiratory pathogens collected during 2000–2001: a comparison with other ß-lactam agents

Mark E. Jones1,*, Renée S. Blosser-Middleton2, Ian A. Critchley2, James A. Karlowsky2, Clyde Thornsberry3 and Daniel F. Sahm2

Focus Technologies, Inc., 1 Koninginneweg 11, Hilversum 1217 KP, The Netherlands; 2 Herndon, VA; 3 Franklin, TN, USA

The first 10% of the full text of this article appears below.

Sir,

Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis comprise the most common causative agents of respiratory tract infections (RTIs). Resistance to penicillin and other ß-lactam agents commonly used as empirical therapies to treat RTIs is an established concern. This has prompted the development of new oral agents that can be used to treat RTIs in both adult and paediatric patients. Faropenem, an investigational compound, the first in the furanem class of compounds intended for oral administration and sharing structural similarities with ß-lactams, has been shown to exhibit broad-spectrum . . . [Full Text of this Article]

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