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JAC Advance Access originally published online on November 1, 2002
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Journal of Antimicrobial Chemotherapy (2002) 50, 1090-1091
© 2002 The British Society for Antimicrobial Chemotherapy

Correspondence

Emergence of two oxacillin-susceptible mecA-positive Staphylococcus aureus clones in a Greek hospital

E. Petinaki, F. Kontos and A. N. Maniatis*

Department of Microbiology, Medical School, University of Thessalia, Papakyriazi 22, Larissa, Greece

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Sir,

Methicillin resistance in Staphylococcus aureus (MRSA) isolates is due to the acquisition of the mecA gene, which encodes the low-affinity penicillin-binding protein PBP2a.1 The NCCLS breakpoint for oxacillin resistance is >=4 mg/L for S. aureus.2 Although sometimes S. aureus isolates expressing borderline resistance (MIC 2 mg/L) carry the mecA gene, isolates possessing the mecA gene but susceptible to oxacillin (MIC . . . [Full Text of this Article]


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