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Journal of Antimicrobial Chemotherapy (2002) 49, 573-574
© 2002 The British Society for Antimicrobial Chemotherapy

Correspondence

Identification of a cassette-borne dfrA7-like gene that shows a 97 bp extension at the 3'-end of the reading frame

Kayode K. Ojoa,b, Diana E. Waturangia,c, H. Akin Odelolab, Antonius Suwantoc,d and Stefan Schwarza,*

a Institut für Tierzucht und Tierverhalten, Bundesforschungsanstalt für Landwirtschaft (FAL), Dörnbergstrasse 25-27, 29223 Celle, Germany; b Department of Pharmaceutical Microbiology and Clinical Pharmacy, College of Medicine, University of Ibadan, Nigeria; c Department of Biology, Faculty of Science and Mathematics, IUC Biotechnology, Bogor Agricultural University, Bogor; d South East Asian Regional Center for Tropical Biology (SEAMEO-BIOTROP), Bogor, Indonesia

Sir,

Sulphonamides and trimethoprim are among the most frequently used antimicrobial drugs in Nigeria, where the combination of both drugs is used preferentially for the treatment of urinary tract infections. However, sulphonamides and trimethoprim are commonly available, alone or in combination, over the counter in pharmacies in Nigeria without a doctor's prescription. Self-medication and misuse of these drugs favours the development of resistance to sulphonamides and trimethoprim in various bacterial pathogens.

During the course of a study on antimicrobial resistance in uropathogenic Escherichia coli from humans in Nigeria, the multi-resistant E. coli strain UCH10386 was obtained from a . . . [Full Text of this Article]

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