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Journal of Antimicrobial Chemotherapy (2002) 49, 425-427
© 2002 The British Society for Antimicrobial Chemotherapy

Correspondence

Low level resistance to oleandomycin as a marker of ermA in staphylococci

Vicenza Di Modugnoa, Massimo Guerrinia, Saroj Shahb and Jeremy Hamilton-Millerb,*

a Department of Microbiology, Research Laboratories, GlaxoSmithKline Medicines Research Centre, via Fleming 4, Verona 37135, Italy; b Department of Medical Microbiology, Royal Free and University College Medical School, London NW3 2PF, UK

Sir,

During a study of the activity of the ketolide telithromycin against staphylococci,1 we identified two subgroups within the inducible MLSB phenotype. Such strains are routinely recognized by being resistant to erythromycin and susceptible to clindamycin, but resistance to the latter is induced by erythromycin. There were 129 strains with this phenotype: in 114 (subgroup 1) both erythromycin and oleandomycin always induced . . . [Full Text of this Article]

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