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Journal of Antimicrobial Chemotherapy (2002) 49, 421-422
© 2002 The British Society for Antimicrobial Chemotherapy

Brief report

Rifabutin-induced cystoid macular oedema

J. D. Vaudaux and Y. Guex-Crosier,*

Jules Gonin Eye Hospital, University Department of Ophthalmology, Avenue de France 15, 1004 Lausanne, Switzerland

Rifabutin is a semi-synthetic antimycobacterial agent mainly used in the treatment of Mycobacterium avium-complex (MAC) in AIDS patients. Rifabutin-induced anterior uveitis has been reported previously. We report the case of a rifabutin-induced cystoid macular oedema (CMO) in an immunocompetent patient with pulmonary MAC infection. As far as we know, CMO secondary to rifabutin therapy has not been described previously.

* Corresponding author. Tel: +41-21-626-8230; Fax: +41-21-626-8122; E-mail: yan.guex{at}ophtal.vd.ch


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