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Journal of Antimicrobial Chemotherapy (2002) 49, 399-401
© 2002 The British Society for Antimicrobial Chemotherapy

Brief report

In vitro activity of telithromycin against Streptococcus pneumoniae resistant to other antibiotics, including cefotaxime

Peter C. Fuchs,*, Arthur L. Barry and Steven D. Brown

The Clinical Microbiology Institute, 9725 SW Commerce Circle, Wilsonville, OR 97070, USA

A total of 407 isolates of Streptococcus pneumoniae, most of which were resistant to one or more antibiotics, were tested for susceptibility to telithromycin and four other agents. Telithromycin was the most active agent tested, with 98% of isolates susceptible to <=1.0 mg/L. For strains resistant to the other antibiotics, susceptibility to telithromycin ranged from 98.6% for strains resistant to trimethoprim/sulfamethoxazole to 94.4% for strains resistant to cefotaxime.

* Corresponding author. Tel: +1-503-682-3232; Fax: +1-503-682-2065; E-mail: cmi{at}hevanet.com


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