Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (12)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Horcajada, J. P.
Right arrow Articles by Mensa, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Horcajada, J. P.
Right arrow Articles by Mensa, J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of Antimicrobial Chemotherapy (2002) 49, 55-59
© 2002 The British Society for Antimicrobial Chemotherapy

Molecular epidemiology and evolution of resistance to quinolones in Escherichia coli after prolonged administration of ciprofloxacin in patients with prostatitis

Juan P. Horcajadaa,*, Jordi Vilab, Antonio Moreno-Martíneza, Joaquim Ruizb, Jose Antonio Martíneza, Miquel Sánchezc, Eladio Sorianoa and Josep Mensaa

a Departments of Infectious Diseases and b Microbiology, Institut Clínic d'Infeccions i Immunologia (ICII) and c Department of Internal Medicine, Hospital Clínic Universitari, Villarroel 170, 08036 Barcelona, Spain

The emergence and evolution of quinolone-resistant Escherichia coli in faeces of patients with prostatitis treated with high-dose oral ciprofloxacin for 1 month were studied. In 11 of 23 patients, from whom only quinolone-susceptible E. coli was isolated before treatment, quinolone-resistant strains, genetically distinct from the quinolone-susceptible ones, predominated during and just after therapy. Two months after treatment, these were completely displaced by quinolone-susceptible E. coli, genetically distinct from the E. coli isolated before and during therapy. Hence, during ciprofloxacin therapy, half of the patients were transiently colonized with new, quinolone-resistant strains of E. coli.

* Corresponding author. Tel: +34-93-2275586; Fax: +34-93-4514438; E-mail: jhorcaja{at}clinic.ub.es


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Antimicrob. Agents Chemother.Home page
M. J. Pultz, M. M. Nerandzic, U. Stiefel, and C. J. Donskey
Emergence and Acquisition of Fluoroquinolone-Resistant Gram-Negative Bacilli in the Intestinal Tracts of Mice Treated with Fluoroquinolone Antimicrobial Agents
Antimicrob. Agents Chemother., September 1, 2008; 52(9): 3457 - 3460.
[Abstract] [Full Text] [PDF]

Home page
 Antimicrob. Agents Chemother.Home page
E. Lautenbach, P. Tolomeo, X. Mao, N. O. Fishman, J. P. Metlay, W. B. Bilker, and I. Nachamkin
Duration of Outpatient Fecal Colonization Due to Escherichia coli Isolates with Decreased Susceptibility to Fluoroquinolones: Longitudinal Study of Patients Recently Discharged from the Hospital
Antimicrob. Agents Chemother., November 1, 2006; 50(11): 3939 - 3943.
[Abstract] [Full Text] [PDF]

Home page
 J Antimicrob ChemotherHome page
K. Gupta, T. M. Hooton, and W. E. Stamm
Isolation of fluoroquinolone-resistant rectal Escherichia coli after treatment of acute uncomplicated cystitis
J. Antimicrob. Chemother., July 1, 2005; 56(1): 243 - 246.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.