Journal of Antimicrobial Chemotherapy (2001) 48, 713-715
© 2001 The British Society for Antimicrobial Chemotherapy
Brief report |
Effect of the growth medium on the in vitro antifungal activity of micafungin (FK-463) against clinical isolates of Candida dubliniensis
a Department of Paediatrics, b Institute for Molecular Biology of Infection, and c Institute for Hygiene and Microbiology, University of Würzburg, Josef-Schneider-Strasse 2, D-97080 Würzburg, Germany
Micafungin (FK-463), a member of the new candin family of antifungal agents, was highly active against clinical isolates of Candida albicans and Candida dubliniensis. The in vitro activity of micafungin suggested that it was more potent than fluconazole, flucytosine, amphotericin B or voriconazole against C. albicans, and comparable or moderately less effective against C. dubliniensis isolates when high-resolution medium (HR) was used. Lower MICs of micafungin were recorded when RPMI 2% or AM3 2% media were used, indicating an influence of the growth medium on the MIC.
* Corresponding author. Tel: +49-931-201-3728; Fax: +49-931-201-3720; E-mail: fmmueller{at}mail.uni-wuerzburg.de
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  I. Varga, G. Soczo, G. Kardos, and L. Majoros Time-kill studies investigating the killing activity of caspofungin against Candida dubliniensis: comparing RPMI-1640 and antibiotic medium 3 J. Antimicrob. Chemother., July 1, 2008; 62(1): 149 - 152. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Canton, J. Peman, M. Sastre, M. Romero, and A. Espinel-Ingroff Killing Kinetics of Caspofungin, Micafungin, and Amphotericin B against Candida guilliermondii. Antimicrob. Agents Chemother., August 1, 2006; 50(8): 2829 - 2832. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Fernandez-Torres, A. Carrillo-Munoz, I. Inza, and J. Guarro Effect of culture medium on the disk diffusion method for determining antifungal susceptibilities of dermatophytes. Antimicrob. Agents Chemother., June 1, 2006; 50(6): 2222 - 2224. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Heyn, A. Tredup, S. Salvenmoser, and F.-M. C. Muller Effect of Voriconazole Combined with Micafungin against Candida, Aspergillus, and Scedosporium spp. and Fusarium solani Antimicrob. Agents Chemother., December 1, 2005; 49(12): 5157 - 5159. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Gil-Lamaignere, R. Hess, S. Salvenmoser, K. Heyn, R. Kappe, and F.-M. C. Muller Effect of media composition and in vitro activity of posaconazole, caspofungin and voriconazole against zygomycetes J. Antimicrob. Chemother., June 1, 2005; 55(6): 1016 - 1019. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Fernandez-Torres, I. Inza, and J. Guarro Evaluation of Disk Diffusion Method for Determining Eberconazole Susceptibility of Dermatophytes and Influence of Culture Medium Antimicrob. Agents Chemother., May 1, 2005; 49(5): 2116 - 2118. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. L Carver Micafungin Ann. Pharmacother., October 1, 2004; 38(10): 1707 - 1721. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Arikan, P. Yurdakul, and G. Hascelik Comparison of Two Methods and Three End Points in Determination of In Vitro Activity of Micafungin against Aspergillus spp. Antimicrob. Agents Chemother., August 1, 2003; 47(8): 2640 - 2643. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. Luque, K. V. Clemons, and D. A. Stevens Efficacy of Micafungin Alone or in Combination against Systemic Murine Aspergillosis Antimicrob. Agents Chemother., April 1, 2003; 47(4): 1452 - 1455. [Abstract] [Full Text] [PDF]
|
|