Journal of Antimicrobial Chemotherapy (2001) 48, 450-451
© 2001 The British Society for Antimicrobial Chemotherapy
Correspondence |
Melaleuca alternifolia (tea tree) oil gel (6%) for the treatment of recurrent herpes labialis
a Department of Microbiology, The University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, WA 6009; b Division of Microbiology and Infectious Diseases, The Western Australian Centre for Pathology & Medical Research, Locked Bag 2009, Nedlands, WA 6909, Australia
Sir,
Recurrent herpes labialis (RHL) or cold sores affect 2040% of the population, some of whom develop frequent attacks.1 Systemic therapy with aciclovir, valaciclovir or famciclovir can suppress or shorten the duration of attacks,2 although the cost of these agents restricts their availability. Topical therapy with aciclovir is popular, although studies assessing the effects of treatment have yielded inconsistent results.3 The essential oil of Melaleuca alternifolia, or tea tree oil (TTO), has broad-spectrum antimicrobial activity in vitro,4 including activity against herpes simplex
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