Journal of Antimicrobial Chemotherapy (2001) 48, 317-319
© 2001 The British Society for Antimicrobial Chemotherapy
Correspondence |
Mechanisms of erythromycin and trimethoprim resistance in the Alaskan Streptococcus pneumoniae serotype 6B clone
a Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK 99508; b Department of Pathobiology, University of Washington, Box 357238, Seattle, WA 98195, USA
Sir,
Clinical isolates of Streptococcus pneumoniae with reduced susceptibility to penicillin have increased worldwide in the past 20 years.1 Parallel to the spread of penicillin resistance has been the increase in resistance to other antibiotics. Although the mechanisms of penicillin resistance are not directly linked with other antibiotic resistance, strains resistant to penicillin are more likely to be resistant to macrolides, trimethoprim/sulfamethoxazole, tetracyclines, clindamycin and chloramphenicol.1 This
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