Journal of Antimicrobial Chemotherapy (2001) 48, 315-316
© 2001 The British Society for Antimicrobial Chemotherapy
Correspondence |
Clindamycin treatment of Staphylococcus aureus expressing inducible clindamycin resistance
a Departments of Microbiology and b Infectious Disease, Auckland Hospital, Auckland, New Zealand
Sir,
We read with interest the correspondence regarding the use of clindamycin in the treatment of patients with infections caused by erythromycin-resistant staphylococci, expressing inducible clindamycin resistance (ICR).1,2 We have been unsure as to the clinical significance of ICR in the treatment of patients with infection due to these organisms. We have recently treated three such patients with clindamycin; two patients were cured but the other was not.
Patient 1, an 87-year-old woman, was admitted with a
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