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Journal of Antimicrobial Chemotherapy (2001) 48, 311-314
© 2001 The British Society for Antimicrobial Chemotherapy

Antimicrobial practice

The efficacy of continuous infusion flucloxacillin in home therapy for serious staphylococcal infections and cellulitis

Benjamin P. Howden,* and Michael J. Richards,{dagger}

Department of Infectious Diseases, Austin and Repatriation Medical Centre, Studley Road, Heidelberg, Victoria 3084, Australia

The efficacy and safety of continuous infusion flucloxacillin as home-based treatment was assessed in 62 consecutive patients with proven serious methicillin-susceptible Staphylococcus aureus (MSSA) infections (n = 36) and cellulitis (n = 26). The treatment was well tolerated and resulted in cure or adequate suppression of infection in 27 of 28 (96%) patients in the serious MSSA infection group, and in 24 of 26 (92%) patients in the cellulitis group.

Correspondence address. Infectious Diseases and Clinical Epidemiology Department, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia. Tel: +61-3-9594-4564; Fax: +61-3-9594-4533; E-mail: Ben.Howden{at}med.monash.edu.au

Present address. Victorian Infectious Disease Service, Royal Melbourne Hospital, Grattan Street, Carlton, Victoria 3053, Australia


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