SHV-type extended-spectrum {beta}-lactamase in a Shigella flexneri clinical isolate

doi:10.1093/jac/47.5.685

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Journal of Antimicrobial Chemotherapy (2001) 47, 685-688
© 2001 The British Society for Antimicrobial Chemotherapy

Brief report

SHV-type extended-spectrum ß-lactamase in a Shigella flexneri clinical isolate

Nicolas Fortineau^a^,*, Thierry Naas^a, Olivier Gaillot^b and Patrice Nordmann^a

^a Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre; ^b Service de Bactériologie-Virologie, Centre Hospitalier et Universitaire de Rennes 35033 Rennes, France

A Shigella flexneri isolate resistant to oxyimino-cephalosporinswas recovered from a stool sample of a 16 month-old Algerianchild hospitalized in Paris, France. This isolate harbouredan SHV-2 ß-lactamase gene located on a c. 80 kb self-transferableplasmid. This is the first report of an Ambler class A extended-spectrumß-lactamase from Shigella spp.

^* Corresponding author. Tel: +33-1-45-21-20-19; Fax: +33-1-45-21-63-40;E-mail: nicolas.fortineau{at}bct.ap-hop-paris.fr

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