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Journal of Antimicrobial Chemotherapy (2001) 47, 495-496
© 2001 The British Society for Antimicrobial Chemotherapy

Correspondence

Current status of the aadA and dfr gene cassette families

Peter A. White,* and William D. Rawlinson

Virology Division, Department of Microbiology, SEALS, Prince of Wales Hospital, Randwick, Sydney, NSW 2031, Australia

Sir,

Antibiotic-resistant microorganisms have significantly compromised antibiotic treatment. A large proportion of resistance in Gram-negative bacteria can be attributed to resistance gene cassettes contained within a site-specific recombination system, termed the integron.1 Mobile cassettes contain genes that confer resistance to nearly every major class of antibiotic and some disinfectants. New gene . . . [Full Text of this Article]

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