Journal of Antimicrobial Chemotherapy (2001) 47, 239-240
© 2001 The British Society for Antimicrobial Chemotherapy
Correspondence |
Resistance to tetracycline and distribution of tetracycline resistance genes in European Staphylococcus aureus isolates
a Institute for Medical Microbiology and Virology, Heinrich-Heine University Düsseldorf, Düsseldorf, Universitätsstrasse 1. Geb. 22.21, 40225 Düsseldorf, Germany; b Eijkman-Winkler Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
Sir,
We read with great interest the recent article by Trzcinski et al.,1 in which the analysis of the expression of tetracycline resistance in 66 methicillin-resistant Staphylococcus aureus (MRSA) isolates was reported. In that study, they used the polymerase chain reaction (PCR) to screen for the presence of four tetracycline-resistance determinants, tetK, tetL, tetM and tetO. They also determined the MICs of tetracycline, doxycycline and minocycline, with or without preincubation with subinhibitory concentrations of tetracycline or minocycline. Despite the results of their susceptibility tests, Trzcinski et al.1 suggested that all tetracycline-resistant S. aureus isolates also be considered doxycycline
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