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Journal of Antimicrobial Chemotherapy (2001) 47, 215-218
© 2001 The British Society for Antimicrobial Chemotherapy

Brief report

Antimicrobial resistance of Streptococcus pneumoniae isolates in 1999 and 2000 in Madrid, Spain: a multicentre surveillance study

J. Oteo, J. I. Alós and J. L. Gómez-Garcés*

Servicio de Microbiología, Hospital de Móstoles, C/Río Júcar s/n, 28935 Móstoles, Madrid, Spain

Resistance to first-line antimicrobial agents in Streptococcus pneumoniae is increasing worldwide and the new fluoroquinolones may provide a good alternative. The antimicrobial susceptibility to levofloxacin and 13 other antibiotics of 300 isolates of S. pneumoniae, isolated in the Madrid community in 1999 and 2000, was determined. A total of 65.6% of isolates were penicillin intermediate or resistant strains. A high percentage of resistance to macrolides, clindamycin, tetracycline and chloramphenicol was also observed, mainly in penicillin-resistant strains. All but one strain was susceptible to levofloxacin.

* Corresponding author. Tel/Fax: +34-1-647-1917; E-mail: jlgarces{at}microb.net.


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