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Journal of Antimicrobial Chemotherapy (2000) 46, 847-848
© 2000 The British Society for Antimicrobial Chemotherapy

Correspondence

Quinolone-induced QT interval prolongation: a not-so-unexpected class effect

James B. Kahn*

Infectious Disease Research, Ortho-McNeil Pharmaceutical, 1000 Route 202, Box 300, Raritan, NJ 08869-0602, USA

Sir,

I read with great interest Dr Peter Ball's recent leading article on quinolone-induced QT interval prolongation.1 The author's ‘re-examination of the facts’ is an admirable effort to discuss recently highlighted fluoroquinolone safety issues. While agreeing that well-studied, and generally safe, antibiotics should be used for the treatment of infections, regardless of minor QT prolongation effects, I do not agree that this cardiac effect is established as a fluoroquinolone . . . [Full Text of this Article]

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