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Journal of Antimicrobial Chemotherapy (2000) 46, 303-306
© 2000 The British Society for Antimicrobial Chemotherapy


Brief reports

Activity of antibiotics used in human medicine for Campylobacter jejuni isolated from farm animals and their environment in Lancashire, UK

Laura J. V. Piddocka,*, V. Riccia, K. Stanleyb and K. Jonesa

a Antimicrobial Agents Research Group, Division of Immunity and Infection, The Medical School, University of Birmingham, B15 2TT; b Division of Biological Sciences, Lancaster University, Lancaster, LA1 4YQ, UK

A retrospective study of 96 Campylobacter jejuni isolated from farm animals and the environment showed that most were less susceptible than the NCTC type strain to nalidixic acid (MICs 4–32 mg/L), ciprofloxacin (MICs 1–2 mg/L) and erythromycin (MICs 16–64 mg/L), but had similar susceptibility to tetracycline (MICs 4–8 mg/L) and kanamycin (MICs 4–8 mg/L). None had the high MICs of ciprofloxacin (>32 mg/L) or erythromycin (1024 mg/L) typically associated with clinical resistance in this species. Some farms used antimicrobial agents, but there was no obvious association between the use of agents and the susceptibility of the isolates.

* Corresponding author. Tel: +44-121-4146969; Fax: +44-121-4146966; E-mail: l.j.v.piddock{at}bham.ac.uk


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