Journal of Antimicrobial Chemotherapy (2000) 46, 303-306
© 2000 The British Society for Antimicrobial Chemotherapy
Brief reports |
Activity of antibiotics used in human medicine for Campylobacter jejuni isolated from farm animals and their environment in Lancashire, UK
a Antimicrobial Agents Research Group, Division of Immunity and Infection, The Medical School, University of Birmingham, B15 2TT; b Division of Biological Sciences, Lancaster University, Lancaster, LA1 4YQ, UK
A retrospective study of 96 Campylobacter jejuni isolated from farm animals and the environment showed that most were less susceptible than the NCTC type strain to nalidixic acid (MICs 432 mg/L), ciprofloxacin (MICs 12 mg/L) and erythromycin (MICs 1664 mg/L), but had similar susceptibility to tetracycline (MICs 48 mg/L) and kanamycin (MICs 48 mg/L). None had the high MICs of ciprofloxacin (>32 mg/L) or erythromycin (1024 mg/L) typically associated with clinical resistance in this species. Some farms used antimicrobial agents, but there was no obvious association between the use of agents and the susceptibility of the isolates.
* Corresponding author. Tel: +44-121-4146969; Fax: +44-121-4146966; E-mail: l.j.v.piddock{at}bham.ac.uk
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