Genetic basis of natural resistance to erythromycin in Mycoplasma hominis

doi:10.1093/jac/45.4.547

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Journal of Antimicrobial Chemotherapy (2000) 45, 547-548
© 2000 The British Society for Antimicrobial Chemotherapy

Correspondence

Genetic basis of natural resistance to erythromycin in Mycoplasma hominis

Pio Maria Furneri^a^,*, Giancarlo Rappazzo^b, Maria Pia Musumarra^a, Gianna Tempera^a and Lucia Silvana Roccasalva^a

^a Department of Microbiological and Gynaecological Sciences, and ^b Department of Animal Biology University of Catania, via Androne 81, 95124 Catania, Italy

Sir,

Only a few studies have been reported, so far, on the mechanismsof antibiotic resistance in mycoplasmas, and those have frequentlyinvolved Mycoplasma pneumoniae. Little information is availablein the literature on the mechanisms of macrolide resistancefound in other species of mycoplasmas or ureaplasmas. In a previousstudy it was reported that high-level resistance to erythromycinwas found in a strain of Ureaplasma urealyticum and associatedwith a six-fold reduction in intracellular influx . . . [Full Text of this Article]

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