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Journal of Antimicrobial Chemotherapy (2000) 45, 257-258
© 2000 The British Society for Antimicrobial Chemotherapy

Correspondence

Comparison of the Etest with a conventional agar dilution method in evaluating the in vitro activity of moxifloxacin

J Antimicrob Chemother 2000; 45: 257–258

J. M. Andrews and R. Wise

Department of Antimicrobial Chemotherapy, City Hospital NHS Trust, Dudley Road, Birmingham B18 7QH, UK

Sir,

The Etest was introduced in 1988 as an alternative method of determining MICs. Although it is used principally to confirm resistance, rather than as a primary susceptibility testing method, the pharmaceutical industry is increasingly adopting it as a means of evaluating new antimicrobial agents, these data being used to confirm or suggest tentative MIC breakpoints. In the present study we have compared the MICs of moxifloxacin determined by two methodologies: according to recommendations of the British Society for Antimicrobial Chemotherapy (BSAC),1 and with the Etest adapted for use in the . . . [Full Text of this Article]

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