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Journal of Antimicrobial Chemotherapy (1999) 44, 693-695
© 1999 The British Society for Antimicrobial Chemotherapy

Brief report

In-vitro activity of antibiotics against Legionella pneumophila isolates from water systems

A. Tsakris*, S. Alexiou-Daniel, E. Souliou and A. Antoniadis

Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54 006 Thessaloniki, Greece

The activity of five antibiotics was tested against 82 isolates of Legionella pneumophila obtained from water systems in nine European countries. All isolates were susceptible to clarithromycin (MICs 0.03–0.5 mg/L), erythromycin (MICs 0.125–2.0 mg/L), ciprofloxacin (MICs 0.06–0.25 mg/L), pefloxacin (MICs 0.06–0.5 mg/L) and rifampicin (MICs <= 0.007–0.015 mg/L). It seems that antibiotics used for legionellosis continue to exhibit good activity against L. pneumophila isolates from environmental sources in European countries.

* Corresponding author. Tel:+30-31-99-91-49; E-mail: atsakris{at}med.auth.gr


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