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Journal of Antimicrobial Chemotherapy (1999) 44, 577-580
© 1999 The British Society for Antimicrobial Chemotherapy

Correspondence

Discrepancies associated with the measurement of itraconazole serum concentrations by bioassays

J Antimicrob Chemother 1999; 44: 577–578

Derek Lawa,*, Caroline B. Mooreb and David W. Denningc

a Hyder Environmental, Howard Court, Manor Park, Runcorn WA7 1SJ b Department of Microbiology, Hope Hospital, Salford M6 8HD c Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, Manchester M8 6RL, UK

Sir,

We read with interest the recent paper by Odds et al.,1 as we have performed a similar study in which we measured the concentrations of itraconazole (IT) and its metabolite, hydroxy-itraconazole (HI), in the sera of 40 patients by a bioassay and compared . . . [Full Text of this Article]

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