Journal of Antimicrobial Chemotherapy (1999) 44, 553-555
© 1999 The British Society for Antimicrobial Chemotherapy
Brief report |
In-vitro susceptibility of Aspergillus spp. isolates to amphotericin B and itraconazole
Laboratoire de Parasitologie, Mycologie Médicale et Pathologie Exotique, Université Claude Bernard Lyon I, 8 avenue Rockefeller, 69373 Lyon Cedex, France
The MICs of amphotericin B and itraconazole for 230 isolates of Aspergillus spp., comprising 156 Aspergillus fumigatus, 20 Aspergillus terreus, 22 Aspergillus flavus, 17 Aspergillus nidulans and 15 Aspergillus niger, were determined by a broth microdilution method with RPMI 1640 medium. No isolate was detected with an MIC of amphotericin B >2 mg/L. Itraconazole MICs >16 mg/L were detected for four Aspergillus fumigatus and one Aspergillus nidulans isolates.
* Corresponding author. Tel: +33-4-78-77-72-18; Fax: +33-4-78-75-17-72; E-mail: edanna{at}rockefeller.univ-lyon1.fr
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