Journal of Antimicrobial Chemotherapy (1999) 43, 729-731
© 1999 The British Society for Antimicrobial Chemotherapy
Brief report |
Reduced susceptibility to vancomycin of nosocomial isolates of methicillin-resistant Staphylococcus aureus
a Department of Microbiology, Medical School, University of Athens, 115 27 Athens, Greece; b Department of Hygiene and Epidemiology, Medical School, University of Athens, 115 27 Athens, Greece
The MICs of vancomycin for 56 random nosocomial Staphylococcus aureusisolates homogeneously resistant to methicillin (homMRSA), 16 heterogeneously resistant isolates (hetMRSA) and 25 susceptible isolates (MSSA) were determined by a standard broth microdilution method. Representative isolates were also tested by an agar incorporation method, the Etest and population analysis. Although always in the susceptible range, MICs of vancomycin for homMRSA were significantly higher than those for hetMRSA or MSSA. Moreover, a homMRSA strain belonging to one of the major Greek MRSA clones contained a sub-population of cells that could grow in the presence of vancomycin 8 mg/L at a frequency of 6.7 x10-8.
* Tel: +30-1-777-1165; Fax: +30-1-770-4225; E-mail: avatopou{at}atlas.uoa.gr
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  G. Wang, J. F. Hindler, K. W. Ward, and D. A. Bruckner Increased Vancomycin MICs for Staphylococcus aureus Clinical Isolates from a University Hospital during a 5-Year Period J. Clin. Microbiol., November 1, 2006; 44(11): 3883 - 3886. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Liu and H. F. Chambers Staphylococcus aureus with Heterogeneous Resistance to Vancomycin: Epidemiology, Clinical Significance, and Critical Assessment of Diagnostic Methods Antimicrob. Agents Chemother., October 1, 2003; 47(10): 3040 - 3045. [Full Text] [PDF]
|
|
|
|
|
|
A. Van Griethuysen, A. Van 't Veen, A. Buiting, T. Walsh, and J. Kluytmans High Percentage of Methicillin-Resistant Staphylococcus aureus Isolates with Reduced Susceptibility to Glycopeptides in The Netherlands J. Clin. Microbiol., June 1, 2003; 41(6): 2487 - 2491. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Aires de Sousa, C. Bartzavali, I. Spiliopoulou, I. Santos Sanches, M. I. Crisostomo, and H. de Lencastre Two International Methicillin-Resistant Staphylococcus aureus Clones Endemic in a University Hospital in Patras, Greece J. Clin. Microbiol., May 1, 2003; 41(5): 2027 - 2032. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. J. Dajcs, B. A. Thibodeaux, D. O. Girgis, M. D. Shaffer, S. M. Delvisco, and R. J. O'Callaghan Immunity to Lysostaphin and Its Therapeutic Value for Ocular MRSA Infections in the Rabbit Invest. Ophthalmol. Vis. Sci., December 1, 2002; 43(12): 3712 - 3716. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. G. Leid, M. E. Shirtliff, J. W. Costerton, and a. P. Stoodley Human Leukocytes Adhere to, Penetrate, and Respond to Staphylococcus aureus Biofilms Infect. Immun., November 1, 2002; 70(11): 6339 - 6345. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. Denis, C. Nonhoff, B. Byl, C. Knoop, S. Bobin-Dubreux, and M. J. Struelens Emergence of vancomycin-intermediate Staphylococcus aureus in a Belgian hospital: microbiological and clinical features J. Antimicrob. Chemother., September 1, 2002; 50(3): 383 - 391. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Trakulsomboon, S. Danchaivijitr, Y. Rongrungruang, C. Dhiraputra, W. Susaemgrat, T. Ito, and K. Hiramatsu First Report of Methicillin-Resistant Staphylococcus aureus with Reduced Susceptibility to Vancomycin in Thailand J. Clin. Microbiol., February 1, 2001; 39(2): 591 - 595. [Abstract] [Full Text]
|
|
|
|
|
|
E. B. H. Hume, J. J. Dajcs, J. M. Moreau, and R. J. O'Callaghan Immunization with Alpha-Toxin Toxoid Protects the Cornea against Tissue Damage during Experimental Staphylococcus aureus Keratitis Infect. Immun., October 1, 2000; 68(10): 6052 - 6055. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. Chesneau, A. Morvan, and N. E. Solh Retrospective screening for heterogeneous vancomycin resistance in diverse Staphylococcus aureus clones disseminated in French hospitals J. Antimicrob. Chemother., June 1, 2000; 45(6): 887 - 890. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. J. Dajcs, E. B. H. Hume, J. M. Moreau, A. R. Caballero, B. M. Cannon, and R. J. O’Callaghan Lysostaphin Treatment of Methicillin-Resistant Staphylococcus aureus Keratitis in the Rabbit Invest. Ophthalmol. Vis. Sci., May 1, 2000; 41(6): 1432 - 1437. [Abstract] [Full Text]
|
|