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Journal of Antimicrobial Chemotherapy (1999) 43, 607-608
© 1999 The British Society for Antimicrobial Chemotherapy

Correspondence

Identification of oprG, a gene encoding a major outer membrane protein of Pseudomonas aeruginosa

J Antimicrob Chemother 1999; 43: 607–608

Karl Gensberga, Anthony W. Smithb, Fiona S. L. Brinkmanc and Robert E. W. Hancockc,*

a Department of Surgery, Queen Elizabeth Hospital, Birmingham, UK b Department of Pharmacy and Pharmacology, University of Bath, Bath, UK c Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada

Sir,

Pseudomonas aeruginosa expresses between five and nine major outer membrane proteins (OMPs), depending on theconditions of growth; 1,2 the genes encoding all but one of these, OprG, have been identified. OprG has an apparentmolecular weight of 25,000 when outer membranes are heated to 88°C for 10 min insolubilization buffer before being subjected to SDS–PAGE and 19,000 when they are . . . [Full Text of this Article]

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