Journal of Antimicrobial Chemotherapy (1999) 43, 313
© 1999 The British Society for Antimicrobial Chemotherapy
Correspondence |
The influence of factors affecting the `critical population' density of inocula on the determination of bacterial susceptibility to antibiotics by disc diffusion methods
J Antimicrob Chemother 1999; 43: 313
Department of Pathology and Microbiology, School of Medical Sciences, University Walk, Bristol BS8 1TD, UK
Sir,
The recent article by Gosden et al.
1 prompted me to reflect on the widespread use of disc
diffusion methods for determining antibiotic susceptibility that ignore an important finding of the
definitive studies of Cooper
2 and Linton
3 on the formation of inhibition zones. These investigators
showed
Notes
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