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Journal of Antimicrobial Chemotherapy (1999) 43, 141-143
© 1999 The British Society for Antimicrobial Chemotherapy

Brief reports

Study to assess the reliability of a disc diffusion method for determining the sensitivity of Gram-positive pathogens to dalfopristin/quinupristin

J. M. Andrews, J. P. Ashby and R. Wise

Department of Medical Microbiology, City Hospital NHS Trust, Birmingham B18 7QH, UK

Abstract

A standardized method of disc testing the sensitivity of Gram-positive pathogens to dalfopristin/quinupristin was developed, and then `field tested' in ten centres in the UK. For a 15 µg disc, zone diameter breakpoints of 20 mm and 15 mm are suggested when organisms are tested on Iso-Sensitest agar and Iso-Sensitest agar supplemented with 5% whole horse blood, respectively.


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