Journal of Antimicrobial Chemotherapy, Vol 40, 895-897, Copyright © 1997 by The British Society for Antimicrobial Chemotherapy
D van de Beek, EF Hensen, L Spanjaard, J de Gans, RH Enting and J Dankert
In-vitro susceptibility of 299 Neisseria meningitidis and 157 Streptococcus
pneumoniae strains from meningitis patients in The Netherlands in 1993 and
1994 to meropenem was determined using the Etest. Susceptibility to
penicillin, ceftriaxone, and chloramphenicol was also determined.
Rifampicin susceptibility was additionally tested for N. meningitidis. Of
the meningococci, 4.3% were of intermediate resistance to penicillin and
0.3% were resistant to rifampicin. One pneumococcal isolate (0.6%) was of
intermediate resistance to penicillin. All strains were susceptible to
meropenem. We conclude that meropenem is in vitro highly active against N.
meningitidis and S. pneumoniae.
ORIGINAL ARTICLES
Meropenem susceptibility of Neisseria meningitidis and Streptococcus pneumoniae from meningitis patients in The Netherlands
The Netherlands Reference Laboratory for Bacterial Meningitis, Academic Medical Center, Amsterdam.
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