Journal of Antimicrobial Chemotherapy, Vol 40, 595-598, Copyright © 1997 by The British Society for Antimicrobial Chemotherapy
CH Steffee, RM Morrell and BL Wasilauskas
Increased use of rifampicin for in-patients was noted after the laboratory
began reporting rifampicin susceptibilities routinely for all Gram-positive
bacterial isolates. The appropriateness of rifampicin use was evaluated by
chart review for in-patients administered rifampicin during two time
periods, before and during routine rifampicin susceptibility reporting,
respectively. While rifampicin susceptibility was reported routinely, four
patients were subjected to potentially harmful misuse of rifampicin. These
findings reconfirm the necessity of interdepartmental consultation and
extensive staff education whenever a modification of antimicrobial
susceptibility profile reporting is contemplated. Furthermore, they
underscore the role of the clinical microbiology laboratory in guiding
antimicrobial therapy through limited reporting of susceptibility data.
ORIGINAL ARTICLES
Clinical use of rifampicin during routine reporting of rifampicin susceptibilities: a lesson in selective reporting of antimicrobial susceptibility data
Department of Pathology, Bowman Gray School of Medicine, Winston-Salem, NC 27157, USA. steffee@bgsm.edu
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