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Journal of Antimicrobial Chemotherapy, Vol 39, 815-816, Copyright © 1997 by The British Society for Antimicrobial Chemotherapy


JOURNAL ARTICLE

Lack of resistance to erythromycin, rifampicin and ciprofloxacin in 98 clinical isolates of Legionella pneumophila

C Onody, P Matsiota-Bernard and C Nauciel
Laboratoire de Microbiologie, Hopital Raymond Poincare, Garches, France.

Ninety-eight consecutive clinical isolates of Legionella pneumophila were tested for erythromycin, rifampicin and ciprofloxacin susceptibility. MICs, determined by agar dilution testing, were in the range 0.06-1 mg/L of erythromycin, 0.007-0.015 mg/L of rifampicin and 0.015-0.03 mg/L of ciprofloxacin. No resistance against the antibiotics tested was detected. It is thus likely that therapeutic failures in legionnaires' disease are not related to the emergence of resistance against commonly used antimicrobial agents.
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