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Journal of Antimicrobial Chemotherapy (1996) 37, 371-375
© 1996 The British Society for Antimicrobial Chemotherapy

brief-report

In-vitro antimicrobial susceptibility of the ‘Streptococcus milleri’ group (Streptococcus anginosus, Streptococcus constellatus and Streptococcus intermedius)

Jan A. Jacobs* and Ellen E. Stobberingh

University Hospital of Maastricht, Department of Medical Microbiology P.O. Box 5800, NL-6202, AZ Maastricht, The Netherlands

Received 22 March 1995; accepted 12 September 1995

A collection of 423 clinical ‘Streptococcus milleri’ strains was speciated and tested for susceptibilities to twelve antibiotics. Only 1.4% of the strains were of intermediate susceptibility to penicillin. None of the strains exhibited high-level resistance to gentamicin. Strains resistant to erythromycin, roxithromycin and clindamycin were found with a frequency of 2.6%, 2.4% and 2.4% respectively. Doxycycline resistance was found in 5.7% of the strains and occurred most frequently in Streptococcus anginosus. All the strains were susceptible to cefotaxime, vancomycin and teicoplanin. The results of this study do not indicate changing antibiotic resistance in strains of the ‘S. milleri’ group, but local differences in antibiotic susceptibilities may occur.


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