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Journal of Antimicrobial Chemotherapy (1985) 16, 397-399
© 1985 The British Society for Antimicrobial Chemotherapy

other

Influence of growth phase on the susceptibility of Candida albicans to butoconazole, oxiconazole, and sulconazole

William H. Beggs

General Medical Research Service (151), Veterans Administration Medical Center Minneapolis, Minnesota 55417, U.S.A.

accepted 17 April 1985

Three topical antifungal imidazoles were examined for fungicidal potential. At 8 x 10–5 M, butoconazole, oxiconazole, and sulconazole were strictly fungistatic against early stationary phase Candida albicans cells diluted into fresh medium. With early logarithmic phase organisms, oxiconazole again was fungistatic, but sulconazole and butoconazole were highly lethal at only 2 x 10–5 M.


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