Table II.. Incidence of pathological changes in various sites of the genital tract of mice from the positive control and treatment regimen groups
|
Percentage (%) of pathological changes
|
| Groups/treatment regimens |
cervico-vaginal |
uterus |
Fallopian tubes |
|
| A. Positive controls (n = 39) |
79.5 |
44.4 |
8.1 |
| B. 3 Dox (n = 68) |
81 |
30.3 |
7.3 |
| C. 3 CaL-Dox (n = 69) |
65.2 |
19.4 |
3 |
| D. 7 Dox (n = 68) |
47.1 |
9.1 |
4.4 |
| E. 7 CaL-Dox (n = 70) |
25.7 |
4.5 |
4.3 |
|
| P = 0.001 for A versus B, C, D, E; P = 0.001 for B versus D; P = 0.02 for B and D versus C and E; and P > 0.05 for C versus D. |
|
