Skip Navigation


JAC Advance Access originally published online on July 3, 2009
Journal of Antimicrobial Chemotherapy 2009 64(3):650-652; doi:10.1093/jac/dkp235
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
64/3/650    most recent
dkp235v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Kinana, A. D.
Right arrow Articles by Piddock, L. J. V.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kinana, A. D.
Right arrow Articles by Piddock, L. J. V.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2009. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Research letters

Contribution of efflux to antibiotic resistance in Campylobacter isolated from poultry in Senegal

Alfred Dieudonné Kinana1,2,*, Vito Ricci3 and Laura J. V. Piddock3

1 Laboratoire de Biologie Médicale, Institut Pasteur de Dakar, BP220, Dakar, Sénégal 2 Unité des Agents Antibactériens, Institut Pasteur, 75724 Paris Cedex 15, France 3 Antimicrobial Agents Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK

* Corresponding author. Tel: +221-33-839-92-00; Fax: +221-33-822-70-52; E-mail: kinana@pasteur.sn

Keywords: mechanisms of resistance , antimicrobial agents , multidrug transporters

The first 10% of the full text of this article appears below.

Sir,

Resistance to antimicrobials in Campylobacter can involve an efflux mechanism. Efflux pumps such as CmeB of Campylobacter can be inhibited directly by inhibitors such as Phe-Arg-β-naphthylamide (PAβN). This inhibitor has been used by others to indicate Campylobacter strains with efflux activity.1 Insertional inactivation of cmeB was shown to increase the susceptibility of Campylobacter to a broad range of antimicrobials.2 The aim of this study was to investigate the involvement of active efflux in the antimicrobial resistance of Campylobacter isolates from Senegal.

Isolates . . . [Full Text of this Article]


   Funding
 

   Transparency declarations
 

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?