JAC Advance Access originally published online on June 17, 2009
Journal of Antimicrobial Chemotherapy 2009 64(3):662-663; doi:10.1093/jac/dkp219
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© The Author 2009. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Research letters |
Toxicokinetics of voriconazole during massive intentional poisoning
1 Thoracic Intensive Care Department, Bordeaux University Hospital, Pessac, France 2 Cardio-pulmonary Transplantation Department, Bordeaux University Hospital, Pessac, France 3 Clinical Pharmacokinetics and Pharmacy Department, Bordeaux University Hospital, Pessac, France
* Corresponding author. SAR 2, Hôpital Haut Lévèque, avenue Magellan, 33600 Pessac, France. Tel: +33-5-57-65-68-66; Fax: +33-5-57-65-68-11; E-mail: hadrien.roze@chu-bordeaux.fr
Keywords: invasive pulmonary aspergillosis , pharmacokinetics , drug toxicity , lung transplantation
| The first 10% of the full text of this article appears below. |
Sir,
We describe the case of a middle-aged man who intentionally poisoned himself with 9.8 g of voriconazole, 60 mg of prednisolone, 4 g of sulfamethoxazole, 2.5 g of azithromycin and 120 mg of bromazepam. This patient with cystic fibrosis had undergone bilateral lung transplantation 7 years previously. He had been
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