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Journal of Antimicrobial Chemotherapy (2002) 50, 1-4
© 2002 The British Society for Antimicrobial Chemotherapy


Leading article

Antimicrobial resistance and susceptibility testing: an evergreen topic

Pietro E. Varaldo*

Department of Microbiology and Biomedical Sciences, University of Ancona Medical School, Via Ranieri, Monte d’Ago, 60131 Ancona, Italy

The first 150 words of the full text of this article appear below.

Few subjects in clinical microbiology are debated as frequently and extensively as antimicrobial susceptibility testing. Nevertheless, few other subjects continue to be considered of such topical interest. Although this is owing to several factors, it mainly reflects on the one hand the continuous technical evolution in this field, and on the other the fact that all such innovations are substantially directed at better assessing antibiotic resistance, which is perceived as a major crisis area of modern medicine.

Little by little, yesterday’s perhaps ingenuous hopes and the early dream of all-powerful antibiotics have been eroded and progressively replaced with deep distrust.1 The repeated warnings of microbial wars,2 new plagues,3 worldwide calamities,4 new apocalypses57 and even an impending post-antimicrobial era8 are a disquieting confirmation of this profound lack of confidence. It is a hard fact that antibiotic resistance is a growing phenomenon, whereas the rate of discovery of new antibiotics has been . . . [Full Text of this Article]


    Acknowledgements
 

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