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Journal of Antimicrobial Chemotherapy (2001) 47, 118-120
© 2001 The British Society for Antimicrobial Chemotherapy

Correspondence

Comparison of serum bactericidal activity of ceftazidime, ciprofloxacin and meropenem against Stenotrophomonas maltophilia

Sebastian W. Lemmena,*, Helga Häfnera, Ralf R. Reinertb, Dirk Zolldanna, Klaus Kümmererc and Rudolf Lüttickenb

a Department of Infection Control, University Hospital Aachen, Germany; b Institute of Medical Microbiology, University Hospital, Aachen, Germany; c Institute for Hygiene and Environmental Medicine, University Hospital, Freiburg, Germany

Sir,

The emergence of Stenotrophomonas maltophilia as a cause of life-threatening disease, particularly in severely immunocompromised patients, is becoming increasingly prominent. S. maltophilia is inherently resistant to multiple antimicrobial agents. A high-dose regimen of cotrimoxazole is the treatment of choice for this infection, but cotrimoxazole resistance has been documented.1 In addition, toxicity of the sulphonamide component of the combination may limit the value of this approach, especially for patients in the intensive care unit. Standard in . . . [Full Text of this Article]

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