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Journal of Antimicrobial Chemotherapy (1999) 43, 845-846
© 1999 The British Society for Antimicrobial Chemotherapy

Correspondence

Electron microscopy studies of the bactericidal effects of quinupristin/dalfopristin on Staphylococcus aureus

J Antimicrob Chemother 1999; 43: 845- 846

Victor Loriana,b,* and Fleance Fernandesa

a The Bronx-Lebanon Hospital Center, Department of Epidemiology and Infection Control, 1650 Selwyn Avenue, Bronx, NY 10457; b Albert Einstein College of Medicine, Bronx, NY, USA

Sir,

Quinupristin/dalfopristin is a combination of two semisynthetic derivatives of pristinamycin which has been shown to have activity in vitro against a wide range of Gram-positive cocci. 1 Preliminary studies in our laboratory of its activity against staphylococci demonstrated that, following exposure to concentrations <MICs, the bacterial cells appeared larger and stained more intensely than controls. A further . . . [Full Text of this Article]

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