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JAC Advance Access originally published online on April 8, 2008
Journal of Antimicrobial Chemotherapy 2008 62(1):189-195; doi:10.1093/jac/dkn143
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Original research

Opposing expectations and suboptimal use of a local antibiotic hospital guideline: a qualitative study

Pieter-Jan Cortoos1,*, Karel De Witte2, Willy E. Peetermans3, Steven Simoens1 and Gert Laekeman1

1 Research Centre for Pharmaceutical Care and Pharmaco-economics, Katholieke Universiteit Leuven, O&N 2, Herestraat 49, PB 521, B-3000 Leuven, Belgium 2 Centre for Organisation and Personnel Psychology, Katholieke Universiteit Leuven, Tiensestraat 102, PB 3725, B-3000 Leuven, Belgium 3 University Hospitals of Leuven, Department of General Internal Medicine and Infectious Diseases, Herestraat 49, PB 7003, B-3000 Leuven, Belgium

Received 20 November 2007; returned 16 January 2008; revised 10 March 2008; accepted 10 March 2008


* Corresponding author. Tel: +32-16-330409; Fax: +32-16-323468; E-mail: pieterjan.cortoos{at}pharm.kuleuven.be

Objectives: The aim of this study was to determine the opinions and problems concerning the use of a local antibiotic hospital guideline in a 1900-bed tertiary-care, university teaching hospital.

Methods: A qualitative study using focus group discussions explored the usability and applicability of local antibiotic guidelines together with possible supportive measures. The sample included 22 physicians, deliberately divided between internal medicine (59.1%) and surgery (40.9%), and levels of experience (59.1% residents; 40.9% supervisors). Focus groups were conducted within one specific subgroup. Analysis was carried out using a framework analysis approach.

Results: General acceptance of local guidelines was high but clear differences were present between subgroups with different desires and requirements from guideline contents. Opposing views were present towards supportive measures, especially multidisciplinary collaboration. Guideline distribution and accessibility appeared to be confusing, resulting in delayed application. An important supplementary barrier was the need to collect the guideline personally. Supervisors in their role as opinion leaders were mentioned as highly influential towards residents' practice.

Conclusions: Locally developed hospital guidelines experience the same barriers as other guidelines. Within one hospital, prescribers have to be seen as a number of different target groups instead of a homogeneous population. For an optimal effect, interventions will have to consider these differences. Also, in order to improve local guideline use and antibiotic consumption, supervisors have to be aware of how their role as opinion leaders can influence residents. Lastly, active guideline distribution and promotion remains critical to ensure efficient guideline use. Future research should focus on how to adapt interventions to these different target groups.

Keywords: antibiotic usage , antibiotic policy , guidelines


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