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JAC Advance Access originally published online on March 26, 2007
Journal of Antimicrobial Chemotherapy 2007 59(5):833-840; doi:10.1093/jac/dkm055
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© The Author 2007. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Review

The ORION statement: guidelines for transparent reporting of Outbreak Reports and Intervention studies Of Nosocomial infection

S. P. Stone1,*, B. S. Cooper1, C. C. Kibbler1, B. D. Cookson2, J. A. Roberts3, G. F. Medley4, G. Duckworth2, R. Lai1, S. Ebrahim3, E. M. Brown5, P. J. Wiffen6 and P. G. Davey7

1 Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK 2 Health Protection Agency, Centre for Infections, Colindale Avenue, Colindale, London NW9 5EQ, UK 3 London School of Hygiene and Tropical Medicine, Keppel Street London WC1E 7HT, UK 4 Warwick University, Coventry CV4 7AL, UK 5 Frenchay Hospital, Bristol BS16 1LE, UK 6 UK Cochrane Centre, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK 7 University of Dundee Medical School Mackenzie Building, Kirsty Semple Way, Dundee DD2 4BF, Scotland, UK


* Corresponding author. Tel: +44-7801258061; Fax: +44-2078302378; E-mail: s.stone{at}medsch.ucl.ac.uk

The quality of research in hospital epidemiology (infection control) must be improved to be robust enough to influence policy and practice. In order to raise the standards of research and publication, a CONSORT equivalent for these largely quasi-experimental studies has been prepared by the authors of two relevant systematic reviews, following consultation with learned societies, editors of journals and researchers. It consists of a 22 item checklist, and a summary table. The emphasis is on transparency to improve the quality of reporting and on the use of appropriate statistical techniques. The statement has been endorsed by a number of professional special interest groups and societies. Like CONSORT, ORION should be considered a ‘work in progress’, which requires ongoing dialogue for successful promotion and dissemination. The statement is therefore offered for further public discussion. Journals and research councils are strongly recommended to incorporate it into their submission and reviewing processes. Feedback to the authors is encouraged and the statement will be revised in 2 years.

Keywords: healthcare-associated infections , hospital epidemiology , evidence-based medicine


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