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JAC Advance Access originally published online on April 10, 2006
Journal of Antimicrobial Chemotherapy 2006 57(6):1055-1064; doi:10.1093/jac/dkl113
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© The Author 2006. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Reviews

Key questions in antiretroviral therapy: Italian Consensus Workshop (2005)

G. Carosi1, C. Torti1,*, M. Andreoni2, G. Angarano3, A. Antinori4, S. Bonora5, M. Borderi6, A. Castagna7, F. Castelli1, R. Cauda8, F. Chiodo6, A. D'arminio-Monforte9, A. De Luca8, G. Di Perri5, F. Dianzani10, G. Filice11, M. Galli12, A. Lazzarin7, F. Maggiolo13, R. Maserati11, F. Mazzotta14, M. Moroni12, C. F. Perno2, V. Vullo4 on behalf of the Members of the Italian HIV Guidelines Working Group{dagger}

1 University of Brescia Brescia, Italy 2 ‘Tor Vergata‘ University Rome, Italy 3 University of Foggia Foggia, Italy 4 INMI Rome, Italy 5 University of Turin Turin, Italy 6 University of Bologna Bologna, Italy 7 Università Vita-Salute S. Raffaele, Milan, Italy 8 Catholic University Rome, Italy 9 Ospedale ‘S. Paolo’ Milan, Italy 10 ‘Campus Biomedico’ Rome, Italy 11 University of Pavia IRCCS Policlinico S. Matteo, Pavia, Italy 12 Ospedale ‘L. Sacco’ Milan, Italy 13 Ospedali Riuniti Bergamo, Italy 14 Ospedale ‘S. Maria Annunziata’ Florence, Italy


*Correspondence address. Clinica di Malattie Infettive e Tropicali, Università degli Studi di Brescia, P. le Spedali Civili 1, I-25123 Brescia, Italy. Tel:+39-030-3996624; Fax: +39-030-303061; E-mail: torti.carlo{at}libero.it

A panel of leading Italian specialists in infectious diseases, virologists and immunologists met in Rome in 2005 to review critical data and discuss recommendations for each of the key questions in antiretroviral therapy today: When to start treatment? How to start? When to switch? What to switch to? Whether to stop or not to stop treatment, and how? The method of a nominal group meeting was used and recommendations were graded for their strength and quality using a system based on the one adopted by the Infectious Diseases Society of America. Main conclusions are summarized and critically discussed in this consensus statement, as well as some of the most recent data supporting these recommendations are provided.

Keywords: HIV , HAART , guidelines


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