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JAC Advance Access originally published online on February 9, 2006
Journal of Antimicrobial Chemotherapy 2006 57(4):609-618; doi:10.1093/jac/dkl024
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© The Author 2006. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Review

Biosurfactants: potential applications in medicine

Lígia Rodrigues1,*, Ibrahim M. Banat2, José Teixeira1 and Rosário Oliveira1

1 Centro de Engenharia Biológica, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal; 2 School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, Northern Ireland, UK

* Corresponding author. Tel: +351-253-604400; Fax: +351-253-678986; E-mail: lrmr{at}deb.uminho.pt

The use and potential commercial application of biosurfactants in the medical field has increased during the past decade. Their antibacterial, antifungal and antiviral activities make them relevant molecules for applications in combating many diseases and as therapeutic agents. In addition, their role as anti-adhesive agents against several pathogens indicates their utility as suitable anti-adhesive coating agents for medical insertional materials leading to a reduction in a large number of hospital infections without the use of synthetic drugs and chemicals. This review looks at medicinal and therapeutic perspectives on biosurfactant applications.

Keywords: antimicrobial activities , antiviral activities , anti-adhesive coatings , therapeutic agents , anti-carcinogenic agents


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