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JAC Advance Access originally published online on March 10, 2005
Journal of Antimicrobial Chemotherapy 2005 55(4):566-569; doi:10.1093/jac/dki051
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© The Author 2005. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions{at}oupjournals.org

Identification of Tet 39, a novel class of tetracycline resistance determinant in Acinetobacter spp. of environmental and clinical origin

Y. Agersø1,* and L. Guardabassi2

1 Danish Institute for Food and Veterinary Research, 1790 Copenhagen V; 2 Department of Veterinary Pathobiology, The Royal Veterinary and Agricultural University, 1870 Frederiksberg C., Denmark

* Corresponding author. Tel: +45-72-34-6273; Fax: +45-72-34-6001; Email: ya{at}dfvf.dk

A novel tetracycline resistance determinant named Tet 39 was found in unrelated Acinetobacter strains isolated from freshwater trout farms (n=4) and sewage (n=6) in Denmark, and from a clinical specimen in the Netherlands (n=1). The determinant was located on transferable plasmids and consisted of tetA(39), most likely conferring resistance by active efflux, and a putative repressor gene tetR(39).

Keywords: tetracycline-resistant , plasmids , tet(39)


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