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JAC Advance Access originally published online on November 12, 2003
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Journal of Antimicrobial Chemotherapy (2003) 52, 1029-1031
© 2003 The British Society for Antimicrobial Chemotherapy

Antibiotic susceptibilities of 94 isolates of Yersinia pestis to 24 antimicrobial agents

Eric Hernandez1,*, Monique Girardet1, Francoise Ramisse2, Dominique Vidal3 and Jean-Didier Cavallo1

1 Hôpital d’iInstruction des armées Bégin, Biologie médicale, Saint-mandé; 2 Centre d’études du Bouchet, Laboratoire de microbiologie, Vert-le-petit; 3 Centre de recherches du service de santé des armées, Laboratoire de microbiologie, La tronche, France

Received 10 April 2003; returned 21 May 2003; revised 13 August 2003; accepted 25 September 2003

Ninety-four isolates of Yersinia pestis collected by the French army between 1964 and 1988 were evaluated for their susceptibilities to 24 antibiotics by the agar dilution method. All the isolates were susceptible to ß-lactam antibiotics including imipenem, to fluoroquinolones, aminoglycosides and to doxycycline. The most active compounds were fluoroquinolone antibiotics, third-generation cephalosporins and aminoglycosides.

Keywords: Y. pestis, antibiotic susceptibility, plague

* Corresponding author. Tel: +33-1-43-98-47-33; Fax: +33-1-43-98-53-36; E-mail: hnz.eric{at}freesurf.fr


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