JAC Advance Access originally published online on September 6, 2002
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Journal of Antimicrobial Chemotherapy (2002) 50, 597-599
© 2002 The British Society for Antimicrobial Chemotherapy
Prevalence of erm(A) and mef(B) erythromycin resistance determinants in isolates of Streptococcus pneumoniae from New Zealand

Plant and Microbial Science Department, University of Canterbury, Christchurch, New Zealand
Received 15 January 2002; returned 7 May 2002; revised 18 June 2002; accepted 8 July 2002
One hundred and twenty-four erythromycin-resistant pneumococcal isolates were examined for the presence of macrolide resistance genes. The erm(B) gene was detected in 118 (95.2%) isolates and the mef(A) gene in 83 (66.9%) isolates. Both the mef(A) and erm(B) genes were detected in 77 (62.1%) isolates. DNA macrorestriction analysis of these isolates identified them as belonging to a single multi-resistant clone.
* Corresponding author. Tel: +064-03-364-2987 (ext. 7169); Fax: +064-364-2083; E-mail: d.bean{at}botn.canterbury.ac.nz
Present address. School of Molecular Biosciences, Washington State University, Pullman, WA, USA.
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