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JAC Advance Access originally published online on September 20, 2002
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Journal of Antimicrobial Chemotherapy (2002) 50, 513-516
© 2002 The British Society for Antimicrobial Chemotherapy

Susceptibility of Danish Escherichia coli strains isolated from urinary tract infections and bacteraemia, and distribution of sul genes conferring sulphonamide resistance

M. B. Kerrn*, T. Klemmensen, N. Frimodt-Møller and F. Espersen

Department of Microbiological R & D, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen, Denmark

Received 25 January 2002; returned 23 April 2002; revised 6 June 2002; accepted 2 July 2002

Antibiotic resistance of urinary tract pathogens has increased worldwide. Our aim was to provide information regarding resistance patterns of Escherichia coli in urinary tract infections (UTIs) and E. coli bacteraemia in Denmark. The overall resistance ranged from: ampicillin 20–47%, mecillinam 0–7%, trimethoprim 10–28%, sulfamethizole 22–47% and nitrofurantoin 0–3%. In strains with sulfamethizole MICs > 2048 mg/L, 97% carried sulI, sulII or both genes, with sulII being the most common. Among the sulI gene-positive strains, 96% were intI 1 gene positive.

* Corresponding author. Tel: +45-32683575; Fax: +45-32683887; E-mail: mbp{at}ssi.dk


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